depressed about physical imperfections and premature ageing, help?

Posted by: admin  :  Category: Skin Pigmentation Disorders

How do i handle the fact ive aged badly due to life stress & dont look the part anymore?

plus i have physical imperfections, and injured ankle, i sprained it a year ago, had a diagnostic operation, discover that i have laxed, stretched tendons , have to go back in 2 weeks for the results and the next stage , have a feeling their not doing surgery now , my ankles very weak and i have to watch how i walk on it, can easily go over and twist it.
i have an average small penis only 5 inch when erect, not thick in girth either, i only discovered this fact since ive had the internet for 3 years and ive been able to see factual photos and info about guys manhoods, it also has a small head on my manhood not big or broad like most other guys.

i have 2 missing teeth, front, bottom row due to an accident years back.
im balding so my heads shaved short but im not bald.

im 31 multiracial, but i look like an aging white man, i have olive skin slightly, bad pigmentation , open pores , deep frown lines , dark lines under my eyes…..my face looks haggard sometimes and i feel i could easily pass for 41 years old instead.

ive had a hard life, missed out on everything people take for granted — building relationships – being employed , getting qualifications , none of it ever happened yet.

i live with personality disorder and post traumatic stress, rage, aggression problems , agoraphobia , bad anxiety, but im committed to chasing help and have been for years , even though the therapy i want is not available in my area because of crap resources ( one on one psychotherapy )
i have a criminal past going back 7 years ago.

my only goal left in life is to attain a job in IT computers then to move abroad, leave england.

i was once a cute adolescant, a handsome youthful person, a vain perfectionist mentally to.

how can i handle the way lifes dramatically altered my looks ?

Hello again sexy. I mean what do you want us to say to you I already told you that you are a turn on I mean I don’t know may be its only with folk type women like myself.

I am listening to REM and feeling turned on again over you and your gender parts.

You can bathe me feed me and dress me the way it would turn you on.

sorry if I am not very helpful but I am very selfish and you are turning me on. Look I don’t know anything about contacting through yahoo but if you know how contact me and ill make you love yourself again.

35d8d49c8530d59 depressed about physical imperfections  and premature ageing, help?

how do i handle the fact ive aged badly due to life stress & dont look the part anymore?

Posted by: admin  :  Category: Skin Pigmentation Disorders

plus i have physical imperfections, and injured ankle, i sprained it a year ago, had a diagnostic operation, discover that i have laxed, stretched tendons , have to go back in 2 weeks for the results and the next stage , have a feeling their not doing surgery now , my ankles very weak and i have to watch how i walk on it, can easily go over and twist it.
i have an average small penis only 5 inch when erect, not thick in girth either, i only discovered this fact since ive had the internet for 3 years and ive been able to see factual photos and info about guys manhoods, it also has a small head on my manhood not big or broad like most other guys.

i have 2 missing teeth, front, bottom row due to an accident years back.
im balding so my heads shaved short but im not bald.

im 31 multiracial, but i look like an aging white man, i have olive skin slightly, bad pigmentation , open pores , deep frown lines , dark lines under my eyes…..my face looks haggard sometimes and i feel i could easily pass for 41 years old instead.

ive had a hard life, missed out on everything people take for granted — building relationships – being employed , getting qualifications , none of it ever happened yet.

i live with personality disorder and post traumatic stress, rage, aggression problems , agoraphobia , bad anxiety, but im committed to chasing help and have been for years , even though the therapy i want is not available in my area because of crap resources ( one on one psychotherapy )
i have a criminal past going back 7 years ago.

my only goal left in life is to attain a job in IT computers then to move abroad, leave england.

i was once a cute adolescant, a handsome youthful person, a vain perfectionist mentally to.

how can i handle the way lifes dramatically altered my looks ?

let us deal with only one of those – the size of "manhood" shown on the internet is significantly larger than average. So you are not comparing yourself to average.

You are comparing yourself to extra-large, exaggerated, or photo shopped pictures.

35d8d49c8530d59 how do i handle the fact ive aged badly due to life stress & dont look the part anymore?

i cant handle the fact ive aged badly at only 31 can anyone help?

Posted by: admin  :  Category: Skin Pigmentation Disorders

How do i handle the fact ive aged badly due to life stress & dont look the part anymore?

plus i have physical imperfections, and injured ankle, i sprained it a year ago, had a diagnostic operation, discover that i have laxed, stretched tendons , have to go back in 2 weeks for the results and the next stage , have a feeling their not doing surgery now , my ankles very weak and i have to watch how i walk on it, can easily go over and twist it.
i have an average small penis only 5 inch when erect, not thick in girth either, i only discovered this fact since ive had the internet for 3 years and ive been able to see factual photos and info about guys manhoods, it also has a small head on my manhood not big or broad like most other guys.

i have 2 missing teeth, front, bottom row due to an accident years back.
im balding so my heads shaved short but im not bald.

im 31 multiracial, but i look like an aging white man, i have olive skin slightly, bad pigmentation , open pores , deep frown lines , dark lines under my eyes…..my face looks haggard sometimes and i feel i could easily pass for 41 years old instead.

ive had a hard life, missed out on everything people take for granted — building relationships – being employed , getting qualifications , none of it ever happened yet.

i live with personality disorder and post traumatic stress, rage, aggression problems , agoraphobia , bad anxiety, but im committed to chasing help and have been for years , even though the therapy i want is not available in my area because of crap resources ( one on one psychotherapy )
i have a criminal past going back 7 years ago.

my only goal left in life is to attain a job in IT computers then to move abroad, leave england.

i was once a cute adolescant, a handsome youthful person, a vain perfectionist mentally to.

how can i handle the way lifes dramatically altered my looks ?

Man.. I’m you’ve had it hard. I’m feel sorry for you(not like "pity" but more, like, admiration for your strenght. The fact that you still stand tall.)
I’ve not a real answer for you(i don’t think there is one, really) but for your altered looks; beauty accessories. No, it’s not for sissies. And maybie when you get the job you want you will have money enough for plastic surjery? Btw, i don’t like spiders either, i have social anxiety to, i have been in clinical major depressions 2 times and i’m only 16 and i have no real friends that i can hang out with whatsoever. So.. I guess you’re not alone. I will probably have a darn shitty life aswell. But was your life really "darn shitty"? Think about it. I mean, yes, that’s the way you described it. As "darn shitty".. But… Think of the good sides. Really.
I know, it’s a weak and pathetic excuse for an incomplete answer but still. I tried ;) . Oh man, i wish there was some way i could help you, though.. Maaan life sucks and "god" hates each and every one of us.

35d8d49c8530d59 i cant handle the fact ive aged badly at only 31 can anyone help?

AP chemistry question…?

Posted by: admin  :  Category: Skin Pigmentation Disorders

Xeroderma pigmentosum is very rare, inderited disorder. Individuals who have this disorder may suffer from various pigmentation abnormalities and develop skin cancers very readily, particularly after exposure to sunlight. can u suggest a biological explanation for the predisposition of these individuals to develop Skin Cancers so readily?

we all have cells in our body that will become cancer if they lose their inhibitors. Imagine the dormid cancer cell as a circle. The inhibitors are like rays of sunshine all around this circle. When the cell becomes dangerous, is when it loses these inhibitors(rays, like sun rays) around it. This allows the cell to attach to blood supply and reproduce itself…i,e. a cancerous growth. Any abnormality or disorder in pigmentation can cause this normally non-productive cell, that could cause skin cancer, to lose its inhibitors…..all hell could break loose then.
This is the opinion of a mad scientist…..>

Xeroderma pigmentsum?

Posted by: admin  :  Category: Skin Pigmentation Disorders

Xeroderma pigmentsum is a very rare, inheritated disorder. Individuals who have this disorder may suffer from various pigmentation abnormalities and develop skin cancers very readily, particulary after exposure to sunlight. Can you suggest a biological explantion for the predisposition of these individuals to develop Skin Cancers so readily? (Developing hypotheses)

Pathophysiology: The basic defect in XP is in nucleotide excision repair (NER), leading to deficient repair of DNA damaged by UV radiation. This extensively studied process consists of the removal and the replacement of damaged DNA with new DNA. Two types of NER exist: global genome (GG-NER) and transcription coupled (TC-NER). The last decade has seen the cloning of the key elements of NER, and the process has been reconstituted in vitro.

Seven XP repair genes, XPA through XPG, have been identified. These genes play key roles in GG-NER and TC-NER. Both forms of NER include a damage-sensing phase, performed in GG-NER by the product of the XPC gene complexed to another factor. In addition, the XPA gene product has been reported to have an affinity for damaged DNA. Therefore, XPA likely plays a role in the damage-sensing phase as well.

Following detection of DNA damage, an open complex is formed. The XPG gene product is required for the open complex formation. The XPB and XPD gene products are part of a 9-subunit protein complex (TFIIH) that is also needed for the open complex formation. Subsequently, the damaged DNA is removed.

The XPG and XPF genes encode endonucleases; however, the XPF gene product functions as an endonuclease when complexed to another protein. The resulting gap is filled in with new DNA by the action of polymerases. An XP-variant has been described. The defect in this condition is not in NER but is instead in postreplication repair.

Seven complementation groups, XPA-XPG, corresponding to defects in the corresponding gene products of XPA-XPG genes, have been described. These entities occur with different frequencies (eg, XPA is relatively common, whereas XPE is fairly rare), and they differ with respect to disease severity (eg, XPG is severe, whereas XPF is mild) and clinical features. Cockayne syndrome can rarely occur with XPB, XPD, and XPG.

In addition to the defects in the repair genes, UV-B radiation also has immunosuppressive effects that may be involved in the pathogenesis of XP.

Although typical symptoms of immune deficiency, such as multiple infections, are not usually observed in patients with XP, several immunologic abnormalities have been described in the skin of patients with XP. Clinical studies of the skin of patients with XP indicate prominent depletion of Langerhans cells induced by UV radiation. Various other defects in cell-mediated immunity have been reported in XP.

These defects include impaired cutaneous responses to recall antigens, decreased circulating T-helper cells-to-suppressor cells ratio, impaired lymphocyte proliferative responses to mitogen, impaired production of interferon in lymphocytes, and reduced natural killer cell activity.

Can All of these pairs produce both a normal and an albino child? (multiple choice)?

Posted by: admin  :  Category: Skin Pigmentation Disorders

Albinism is a recessive disorder that affects the pigmentation of the skin. A couple has two children. One child has albinism and one is normal. Which one of the following genotype pairs can the parents not be? Let A = normal and a = albinism.

Choices:
Aa × Aa
Aa × AA
Aa × aa
All of these pairs can produce both a normal and an albino child.

the second one. if you do a punnet square you will only get either AA or Aa. assuming that aa is the genotype for albinism, you can’t get any albino children from that crossing.

Mild acne, oily skin and hyper pigmentation/scars?

Posted by: admin  :  Category: Skin Pigmentation Disorders

How am I supposed to deal with all of it? I have tried so many things for my skin I’ve lost count, my mom is even an esthetician and Skin Care specialist (she suggests a visit to the dermatologist and to get prescribed Acutane) because she herself can’t do much to help me with my Acne. I’ve had acne since the beginning of my teens. I know….the hormones, but I’m now almost 20 and is not going away any time soon. As a singer, my skin has to be healthy and good looking for my career. How can I approach this problem step by step and using money reasonably since I’m broke? Maybe using ACUTANE would end my issue? More water? Maybe exercising and eliminating processed foods from my diet completely? Beause I eat pretty healthy, but I also eat other processed foods which may cause me to breakout more often. Should I use supplements? What products can I use that are easy on the skin and all-natural not irrating for my type of skin? Any advice will be appreciated. I’m thinking my acne is due to the hormonal inbalance since I have alot of stress ad suffer from an Anxiety disorder and OCD

for the acne scars, hyper pigmentation…maybe I’ll have to undergoe laser treatment and peeling? What exactly?

thanks for any skin care advice

Hi,

Acne is something that I’m sure everyone is familiar with or has been affected by at some point. However, few experience the kind that I had to deal with – oily, oozing pores, yellow, enormous pus-filled blemishes and cystic acne that made even sleeping painful and difficult. I had pimples and cystic acne all over my face, back, shoulders and chest. I couldn’t wear certain clothes, never wanted to go out and even avoided mirrors.

I’ve tried what seems like literally everything to cure my skin – yet nothing worked. Not to mention the terrifying side effects I was experiencing – drying, peeling skin, mood swings from prescription drugs and increasing amounts of cystic acne.

After reading the book and fully beginning the program, I really began to notice all kinds of changes in myself – inside and out. I was feeling more positive about my skin, and this only increased and continued as I continued with the program – within two months, I felt like a different person. My skin was completely clear, not red at all, with no acne flare-ups since. My attitude has completely changed as well – I’m no longer shy or afraid to go out, and I’m full of confidence.

Most of us have tried: Accutane, Antibiotics, Zenmed, Proactive, Oratin, Benezoyl peroxide, hydrotherapy, aromatherapy, macrobiotics, reflexology, Chinese Medicine, vegetarianism, the Wai diet, magnetic therapy, the mucus-less diet, blood type diet, went to psychiatrists, homeopaths and even healers…Yet we Still Suffered From Severe Acne.

Needless to say most of these methods, treatments and so called cures either made our skin condition and our acne worse and filled us with heart breaking disappointment and frustration or they worked only short term, and acne came back with a vengeance. Some of these treatments simply didn’t have any effect what so ever on our skin condition.

More info at http://www.powerfulremedies.com/acne/53-treatment-people-with-acne-1628

if you were to answer ‘ honestly ‘ – do you think my life is completely hopeless?

Posted by: admin  :  Category: Skin Pigmentation Disorders

im sorry but just lately iam really worrying about it and feel very insecure..
ive had a really rough and unfortunate life and missed out on virtually everything, normal development – an education – building any relationships with people – having a job, being employed – suffered immense hardships from people – bullying , victimisation alot throughout life – have a criminal record going back 8 years ago, landed in psychiatric hospital, been sectioned – been homeless in salvation army for 12 months in 2003 .

thats just a brief summary..

now i have lived in my own 1 bedroom apartment, government housing for 4 years, living on disability owning nothing but the bare essentials and my prize possession, my computer.

ive managed my rage, aggression, conduct for many years now , i used to have regular, countless rage outbursts in public , lashing out at people, i was diagnosed with BPD personality disorder and i have ptsd symptoms to , and bad agoraphobia – im reliant on the local mental health services , and they are offering me an occupational therapist to help me integrate back into society because i have been isolated and alienated from society half my adult life.
im 31 this january , and i have these aspirations for myself still, to get things ive never had, i would like to attain :

good friends , a relationship with oppisite sex , a decent paying IT job , then i would like to relocate and leave england to live some place quiet and coastal, buy my own little home, enough to live on , significant other etc .

but at my stage in life, with my level of disadvantages, im worrying i will never accomplish these goals or it will take to long , as im already 31 , and its worrying me, i have a lot to work through , just the therapy to learn how to get along with people better, which atm is not available because of crap resources so im having to accept the OT.

iam bald so ive shaved my head, i have aged badly , have 2 missing teeth ( front bottom row) because of a grissly accident , bad skin pigmentation , the cute boyish looks have faded , im overweight ( slightly ) out of shape , need my ankle operating on due to a bad sprain a year ago, its very weak, gives way easily.

i obviously have a lot to work through in my life and a long way to go to attain my goals and im already an ‘ old ‘ looking 31 ??? wtf !!!

where am i going to find the fckn strength from to achieve the life i want at many disadvantages ??

as lonely as iam, i cannot just summon friends, a loving wife , a secure IT job tommorrow, as desperate as iam.

what am i going to do ?

congrats on how you’ve far come in life. 31 is still young enough to accomplish your dreams. be strong and be positive and do everythingyou can to help yourself move farther. set yourslf some short term goals, then some 1 year goals then a five year plan, even a 10 year plan. 41 is still young, youve got a whole 10years to make your dream come true. thats more than enough time. oh and this wont save you but nuitrtion is very important for energy mental clarity- which youll need for studying and also can help alleviate mental problems. google patrick holford or the brain bio centre. you CAN do it. i find its good to read inspirational books and watch inspirational dvds. you know where people beat all the odds to do things. you never know you could be writting your own book some day!!!. thing of how much help you could offer people after you’ve made it.

is it completley hopeless for me now?

Posted by: admin  :  Category: Skin Pigmentation Disorders

just lately iam really worrying about it and feel very insecure..
ive had a really rough and unfortunate life and missed out on virtually everything, normal development – an education – building any relationships with people – having a job, being employed – suffered immense hardships from people – bullying , victimisation alot throughout life – have a criminal record going back 8 years ago, landed in psychiatric hospital, been sectioned – been homeless in salvation army for 12 months in 2003 .

thats just a brief summary..

now i have lived in my own 1 bedroom apartment, government housing for 4 years, living on disability owning nothing but the bare essentials and my prize possession, my computer.

ive managed my rage, aggression, conduct for many years now , i used to have regular, countless rage outbursts in public , lashing out at people, i was diagnosed with BPD personality disorder and i have ptsd symptoms to , and bad agoraphobia – im reliant on the local mental health services , and they are offering me an occupational therapist to help me integrate back into society because i have been isolated and alienated from society half my adult life.
im 31 this january , and i have these aspirations for myself still, to get things ive never had, i would like to attain :

good friends , a relationship with opposite sex , a decent paying IT job , then i would like to relocate and leave england to live some place quiet and coastal, buy my own little home, enough to live on , significant other etc .

but at my stage in life, with my level of disadvantages, im worrying i will never accomplish these goals or it will take to long , as im already 31 , and its worrying me, i have a lot to work through , just the therapy to learn how to get along with people better, which atm is not available because of crap resources so im having to accept the OT.

iam bald so ive shaved my head, i have aged badly , have 2 missing teeth ( front bottom row) because of a grisly accident , bad skin pigmentation , the cute boyish looks have faded , im overweight ( slightly ) out of shape , need my ankle operating on due to a bad sprain a year ago, its very weak, gives way easily.

i obviously have a lot to work through in my life and a long way to go to attain my goals and im already an ‘ old ‘ looking 31.

the local community have treated me standoffish and aloof for many years , very non accepting , i get funny looks in supermarkets etc, like they think they know me or are over familiar with my character and see fit to judge me , even though ive manged rage outbursts , for many years now, which i used to have -

im not even in the position to relocate from britain right now which is ultimately what i would like to do eventually, move abroad permanently – i have a lot to work through and dont have the life skills or know how to just take off, – which means im stuck here in this miserable situation for now..

years ago i was defamed and vilified by people thar are no longer in my life but are Still obviously around in society , so i feel that what they said , their influence has circulated around causing society to ostracise me.

where am i going to find the strength from to achieve the life i want at many disadvantages ?

as lonely as iam, i cannot just summon friends, a loving wife , a secure IT job tomorrow, as desperate as iam.

what am i going to do ? iam to scared to commit self extermination so iam trapped in a life that is going to be impossible to work through…

i feel branded and labelled as somebody to avoid , although i dont know this for certain , except i feel it from the local community.

i feel to passionate about my goals to give up but daunted that it will be impossible or to difficult to accomplish.

i definitely dint want to stay in england

i also feel very depress because i feel nobody has had it as bad as me in life and ive had it the worst.

please no condescending answers like you know me or are fit to judge because you no nothing about me , only what i tell you here.

and i dont say this to make others feel sorry for me because i dont like that , i say this because to disclose the full facts about my situation.

As long as you’re alive, there’s no reason to feel hopeless. You have already survived so much — some people would have given up long ago. Have some pride in yourself that you are still sane and contacting others. It might help your emotional state to set one goal for yourself at a time, and when you reach that one, move to the next goal.
Go to a library and look up the life stories of famous comedians and actors; it is amazing how many lost parents when they were young, and had other difficult lives. My point is you have many talents and skills you’re able to share, so one of your goals to keep in mind now is to find your best skill and be able to use it. Stay positive about yourself.

is it completley hopeless for me now?

Posted by: admin  :  Category: Skin Pigmentation Disorders

just lately iam really worrying about it and feel very insecure..
ive had a really rough and unfortunate life and missed out on virtually everything, normal development – an education – building any relationships with people – having a job, being employed – suffered immense hardships from people – bullying , victimisation alot throughout life – have a criminal record going back 8 years ago, landed in psychiatric hospital, been sectioned – been homeless in salvation army for 12 months in 2003 .

thats just a brief summary..

now i have lived in my own 1 bedroom apartment, government housing for 4 years, living on disability owning nothing but the bare essentials and my prize possession, my computer.

ive managed my rage, aggression, conduct for many years now , i used to have regular, countless rage outbursts in public , lashing out at people, i was diagnosed with BPD personality disorder and i have ptsd symptoms to , and bad agoraphobia – im reliant on the local mental health services , and they are offering me an occupational therapist to help me integrate back into society because i have been isolated and alienated from society half my adult life.
im 31 this january , and i have these aspirations for myself still, to get things ive never had, i would like to attain :

good friends , a relationship with opposite sex , a decent paying IT job , then i would like to relocate and leave england to live some place quiet and coastal, buy my own little home, enough to live on , significant other etc .

but at my stage in life, with my level of disadvantages, im worrying i will never accomplish these goals or it will take to long , as im already 31 , and its worrying me, i have a lot to work through , just the therapy to learn how to get along with people better, which atm is not available because of crap resources so im having to accept the OT.

iam bald so ive shaved my head, i have aged badly , have 2 missing teeth ( front bottom row) because of a grisly accident , bad skin pigmentation , the cute boyish looks have faded , im overweight ( slightly ) out of shape , need my ankle operating on due to a bad sprain a year ago, its very weak, gives way easily.

i obviously have a lot to work through in my life and a long way to go to attain my goals and im already an ‘ old ‘ looking 31.

the local community have treated me standoffish and aloof for many years , very non accepting , i get funny looks in supermarkets etc, like they think they know me or are over familiar with my character and see fit to judge me , even though ive manged rage outbursts , for many years now, which i used to have -

im not even in the position to relocate from britain right now which is ultimately what i would like to do eventually, move abroad permanently – i have a lot to work through and dont have the life skills or know how to just take off, – which means im stuck here in this miserable situation for now..

years ago i was defamed and vilified by people thar are no longer in my life but are Still obviously around in society , so i feel that what they said , their influence has circulated around causing society to ostracise me.

where am i going to find the strength from to achieve the life i want at many disadvantages ?

as lonely as iam, i cannot just summon friends, a loving wife , a secure IT job tomorrow, as desperate as iam.

what am i going to do ? iam to scared to commit self extermination so iam trapped in a life that is going to be impossible to work through…

i feel branded and labelled as somebody to avoid , although i dont know this for certain , except i feel it from the local community.

i feel to passionate about my goals to give up but daunted that it will be impossible or to difficult to accomplish.

i definitely dint want to stay in england

i also feel very depress because i feel nobody has had it as bad as me in life and ive had it the worst.

please no condescending answers like you know me or are fit to judge because you no nothing about me , only what i tell you here.

and i dont say this to make others feel sorry for me because i dont like that , i say this because to disclose the full facts about my situation.

As long as you’re alive, there’s no reason to feel hopeless. You have already survived so much — some people would have given up long ago. Have some pride in yourself that you are still sane and contacting others. It might help your emotional state to set one goal for yourself at a time, and when you reach that one, move to the next goal.
Go to a library and look up the life stories of famous comedians and actors; it is amazing how many lost parents when they were young, and had other difficult lives. My point is you have many talents and skills you’re able to share, so one of your goals to keep in mind now is to find your best skill and be able to use it. Stay positive about yourself.